Description

3-(Methoxycarbonyl)Propane-1-Sulphonyl Chloride, Methyl 4-(Chlorosulphonyl)Butyrate is a versatile and highly reactive sulfonyl chloride derivative, essential for introducing the sulfonyl moiety into complex organic molecules. Its core value lies in its dual functional groups, enabling it to act as a key building block in the synthesis of advanced pharmaceutical intermediates and specialty chemicals. This compound is particularly needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing sulfonamides, sulfonate esters, and other functionalized target compounds.

Application

• Pharmaceutical Intermediate Synthesis: A critical reagent for the preparation of active pharmaceutical ingredients (APIs), especially those containing sulfonamide pharmacophores.
• Agrochemical Production: Used in the synthesis of novel herbicides, fungicides, and insecticides where the sulfonyl group enhances biological activity.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating functional polymers with specific surface properties.
• Dye & Pigment Manufacturing: Employed in the synthesis of sulfonated dyes and colorants to improve solubility and fastness properties.
• Ligand & Catalyst Development: Useful for modifying ligands in coordination chemistry and creating novel organocatalysts.
• Custom Chemical Synthesis: A valuable starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.

Basic Information

Product Name	3-(Methoxycarbonyl)Propane-1-Sulphonyl Chloride, Methyl 4-(Chlorosulphonyl)Butyrate
CAS No.	81926-28-5
Molecular Formula	C6H11ClO4S
Molecular Weight	214.67 g/mol
Synonyms	Methyl 4-(Chlorosulfonyl)butyrate; Methyl 4-chlorosulfonylbutyrate; 4-(Chlorosulfonyl)butyric Acid Methyl Ester; 3-(Methoxycarbonyl)-1-propanesulfonyl Chloride; Butyric acid, 4-(chlorosulfonyl)-, methyl ester; Methyl γ-chlorosulfonylbutyrate; 4-(Methoxycarbonyl)butane-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 3-(Methoxycarbonyl)Propane-1-Sulphonyl Chloride adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.