Description

(Methyl-13C)Triphenylphosphonium Iodide is a stable isotope-labeled organophosphorus reagent, specifically a Wittig reagent, where the methyl group is enriched with carbon-13. This compound is essential for introducing a 13C-labeled methylene group into target molecules, enabling precise tracking and quantification in metabolic and mechanistic studies. It is a critical material for researchers and manufacturers in pharmaceutical development, agrochemical research, and advanced material science who require isotopically labeled building blocks for synthesis, NMR spectroscopy, and mass spectrometry applications.

Application

• Synthesis of 13C-Labeled Olefins: Core reagent in Wittig reactions for the preparation of alkenes with a site-specific carbon-13 label.
• Pharmaceutical Intermediate Production: Used in the synthesis of isotopically labeled drug candidates and metabolites for pharmacokinetic and pharmacodynamic (PK/PD) studies.
• Agrochemical Research: Employed in creating labeled versions of pesticides or herbicides to study their environmental fate, degradation pathways, and mode of action.
• Metabolic Pathway Tracing: Key precursor for synthesizing probes used in NMR-based metabolic flux analysis in biological systems.
• Material Science: Building block for creating 13C-labeled polymers or organic electronic materials for structural and dynamic analysis.
• Analytical Standard Development: Serves as a high-purity reference standard for quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy.

Basic Information

Product Name	(Methyl-13C)Triphenylphosphonium Iodide
CAS No.	81826-67-7
Molecular Formula	C19H16*IP (* denotes 13C)
Molecular Weight	Contact for details
Synonyms	Triphenyl(13C-methyl)phosphonium iodide; (13C-Methyl)triphenylphosphonium iodide; Phosphonium, triphenyl(13C-methyl)-, iodide; 13C-Labeled Methyltriphenylphosphonium Iodide; [13C]Methyltriphenylphosphonium Iodide; P(13CH3)Ph3I; Wittig Reagent-13C
EINECS	Contact for details

Quality Control

Our (Methyl-13C)Triphenylphosphonium Iodide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR (1H, 13C, 31P) and HPLC to confirm chemical identity, isotopic enrichment (typically >99 atom % 13C), and high chemical purity. Certificates of Analysis (COA) detailing all specifications are available upon request to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a desiccated environment to maintain stability and prevent degradation. Handle and store under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment (13C NMR)	≥99 atom % 13C
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.