Description

2-(Acetylamino)-1,4:3,6-Dianhydro-2-Deoxy-L-Iditol 5-Nitrate is a specialized chiral intermediate and nitrated sugar derivative of significant interest in advanced organic synthesis. Its value lies in its unique bicyclic isosorbide-like scaffold, which serves as a versatile building block for pharmaceutical research and fine chemical manufacturing. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and high-value chiral molecules.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly those targeting cardiovascular and central nervous system disorders.
• Nitrate Prodrug Development: Serves as a model compound or a core structure for designing prodrugs that utilize nitrate ester groups for controlled nitric oxide release.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or building block to induce stereoselectivity in complex organic transformations.
• Glycomimetics Research: Valuable scaffold for creating sugar mimics (glycomimetics) with potential biological activity.
• Polymer Science: Potential monomer for creating novel biodegradable or functional polymers derived from renewable sugar platforms.
• Agrochemical Synthesis: Intermediate in the development of advanced, chiral active ingredients for crop protection.

Basic Information

Product Name	2-(Acetylamino)-1,4:3,6-Dianhydro-2-Deoxy-L-Iditol 5-Nitrate
CAS No.	81786-24-5
Molecular Formula	C8H10N2O7
Molecular Weight	246.17 g/mol
Synonyms	2-Acetamido-1,4:3,6-dianhydro-2-deoxy-L-iditol 5-nitrate; 5-Nitro-2-(acetylamino)-1,4:3,6-dianhydro-2-deoxy-L-iditol; L-Iditol, 2-(acetylamino)-1,4:3,6-dianhydro-2-deoxy-, 5-nitrate; 2-Deoxy-2-acetamido-1,4:3,6-dianhydro-L-iditol 5-nitrate; Nitrated Isosorbide Acetamide Derivative; 81786-24-5; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 2-(Acetylamino)-1,4:3,6-Dianhydro-2-Deoxy-L-Iditol 5-Nitrate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee reliable and consistent performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.