Description

S(-)-Skf-38393 Hcl is a high-purity, enantiomerically pure chemical compound widely recognized as a selective dopamine D1 receptor agonist. This specificity makes it a critical research tool for studying dopaminergic pathways and their role in neurological functions and disorders. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in neuroscience, pharmacology, and drug discovery.

Application

• Neuroscience Research: A key pharmacological tool for investigating the function and signaling of dopamine D1 receptors in the central nervous system.
• Pharmacological Studies: Used in in vitro and in vivo assays to study receptor binding, activation, and downstream cellular effects.
• Drug Discovery & Development: Serves as a reference standard and lead compound in the development of novel therapeutics targeting neurological and psychiatric conditions.
• Academic & Clinical Research: Facilitates studies on conditions such as Parkinson's disease, schizophrenia, addiction, and cognitive disorders.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) and functional assays to identify and characterize new drug candidates.

Basic Information

Product Name	S(-)-Skf-38393 Hcl
CAS No.	81702-43-4
Molecular Formula	C₁₆H₁₈ClNO₃ • HCl
Molecular Weight	344.23 g/mol (for free base C₁₆H₁₈ClNO₃)
Synonyms	(−)-SKF-38393 hydrochloride; (1R,3S)-1-(3,4-Dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline-7,8-diol hydrochloride; SKF 38393 HCl; S(-)-SKF-38393; SKF-38393 (S enantiomer); Dopamine D1 receptor agonist (S form); 7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride (S enantiomer)
EINECS	Contact for details

Quality Control

Our S(-)-Skf-38393 Hcl is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity, essential for reliable research outcomes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards for research chemicals to guarantee product integrity and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (S enantiomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.