Description

(13E,16S,18R,19E)-7,18-Dihydroxy-10-Phenyl-16,18-Dimethyl-5,6-Didehydro-21,23-Dioxa[13]Cytochalasa-13,19-Diene-1,17,22-Trione is a complex, semi-synthetic derivative of the cytochalasan family of fungal metabolites. This compound is of significant interest for its potential as a highly specific biochemical tool in life science research, particularly in studies of cellular dynamics and cytoskeletal function. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in the discovery of novel therapeutic agents and cellular mechanisms.

Application

• Biochemical Research: As a potent and specific modulator of actin polymerization dynamics for studying cytoskeleton architecture and cell motility.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the synthesis and screening of novel anti-cancer and anti-inflammatory drug candidates.
• Cell Biology Studies: Used to investigate fundamental cellular processes such as endocytosis, vesicle trafficking, and cytokinesis.
• Mechanism of Action (MoA) Studies: Employed as a pharmacological probe to elucidate signaling pathways and validate drug targets related to the cytoskeleton.
• Reference Standard: For analytical method development, validation, and quality control in the production of related cytochalasan compounds.

Basic Information

Product Name	(13E,16S,18R,19E)-7,18-Dihydroxy-10-Phenyl-16,18-Dimethyl-5,6-Didehydro-21,23-Dioxa[13]Cytochalasa-13,19-Diene-1,17,22-Trione
CAS No.	81657-79-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cytochalasin derivative 81657-79-6; 7,18-Dihydroxy-10-phenyl-16,18-dimethyl-5,6-didehydro-21,23-dioxa[13]cytochalasa-13,19-diene-1,17,22-trione; Dioxacytochalasin; [13]Cytochalasa-13,19-diene derivative; Oxacytochalasan; 81657-79-6 (CAS RN); 10-Phenylcytochalasin derivative
EINECS	Contact for details

Quality Control

Our (13E,16S,18R,19E)-7,18-Dihydroxy-10-Phenyl-16,18-Dimethyl-5,6-Didehydro-21,23-Dioxa[13]Cytochalasa-13,19-Diene-1,17,22-Trione is produced under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.