Description

5-Carbamoyl-2-Methoxybenzene-1-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites—the sulfonyl chloride and carbamoyl groups—which enable precise and efficient derivatization for creating complex molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, leveraging the sulfonyl moiety for biological activity.
• Dye and Pigment Manufacturing: Serves as a reactive intermediate for producing specialized azo dyes and colorants.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with sulfone linkages.
• Chemical Research & Development: A versatile reagent for constructing complex organic scaffolds in medicinal and process chemistry.
• Material Science: Used in the surface modification of materials to introduce specific functional groups.

Basic Information

Product Name	5-Carbamoyl-2-Methoxybenzene-1-Sulfonyl Chloride
CAS No.	81592-99-6
Molecular Formula	C8H8ClNO4S
Molecular Weight	249.67 g/mol
Synonyms	2-Methoxy-5-carbamoylbenzenesulfonyl chloride; 3-Methoxy-4-(chlorosulfonyl)benzamide; 5-Aminocarbonyl-2-methoxybenzenesulfonyl chloride; 4-Carbamoyl-2-methoxybenzenesulfonyl chloride; 2-Methoxy-5-sulfamoylbenzoyl chloride (common misnomer); 4-(Chlorosulfonyl)-2-methoxybenzamide; 5-Carbamoyl-2-methoxy-phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Carbamoyl-2-Methoxybenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.