Description

γ-Aminobutyric Acid Hydroxamate is a specialized derivative of the major inhibitory neurotransmitter γ-aminobutyric acid (GABA). This compound is a crucial biochemical tool and synthetic intermediate, valued for its ability to interact with GABAergic systems and serve as a hydroxamate functional group donor. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors for drug discovery, enzyme inhibition studies, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Research & Development: Acts as a key intermediate in the synthesis of potential neuroactive drugs and enzyme inhibitors targeting conditions like anxiety, epilepsy, and sleep disorders.
• Biochemical Research: Serves as a standard or probe in neuroscience studies to investigate GABA receptor subtypes and neurotransmitter metabolism pathways.
• Agrochemical Synthesis: Used as a building block for developing novel crop protection agents that may target specific pest physiologies.
• Enzyme Inhibition Studies: The hydroxamate moiety makes it a valuable candidate for studying metalloprotease and other enzyme inhibition mechanisms.
• Chemical Synthesis: Employed as a versatile synthon for introducing the GABA-hydroxamate pharmacophore into more complex molecular architectures.

Basic Information

Product Name	γ-Aminobutyric Acid Hydroxamate
CAS No.	81485-19-0
Molecular Formula	C5H10N2O3
Molecular Weight	146.15 g/mol
Synonyms	4-Aminobutyric Acid Hydroxamate; GABA Hydroxamate; 4-Aminobutanoic Acid Hydroxamate; 4-Amino-N-hydroxybutyramide; γ-Aminobutyric Hydroxamic Acid; NSC 84145; Butanoic acid, 4-amino-, 1-hydroxyamide
EINECS	Contact for details

Quality Control

Our γ-Aminobutyric Acid Hydroxamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.