Description

(8-Beta)-n-Cyclohexyl-n-((Cyclohexylamino)Carbonyl)-6-(2-Propenyl)Ergo Line-8-Carboxamide CAS NO 81409-86-1 is a complex, semi-synthetic ergoline derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate or a potential pharmacophore for creating novel therapeutics targeting neurological and endocrine pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of new drug candidates, particularly for investigating central nervous system (CNS) disorders and hormonal regulation.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel ergot alkaloid derivatives for preclinical and clinical research.
• Neurological Research: Used as a reference standard or active compound in studies targeting dopamine, serotonin, or adrenergic receptor systems.
• Endocrinology Studies: Applied in research exploring compounds that may influence prolactin secretion or other pituitary functions.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties.
• Reference Standard: Employed in analytical laboratories for method development and validation, including HPLC and LC-MS analysis.
• Biochemical Tool Compound: Utilized in vitro to probe specific biological pathways and mechanisms of action related to ergoline pharmacology.

Basic Information

Product Name	(8-Beta)-n-Cyclohexyl-n-((Cyclohexylamino)Carbonyl)-6-(2-Propenyl)Ergo Line-8-Carboxamide
CAS No.	81409-86-1
Molecular Formula	C30H43N3O2
Molecular Weight	477.69 g/mol
Synonyms	6-Allyl-8β-[[(cyclohexylamino)carbonyl]amino]methyl]-1-methylergoline-8-carboxamide; 8β-(N-Cyclohexyl-N-((cyclohexylamino)carbonyl)carbamoyl)-6-(2-propenyl)ergoline; 6-Allyl-8β-(N-cyclohexylcarbamoylaminomethyl)-1-methylergoline-8-carboxamide; Lergotrile analog; Cyclohexyl ergoline carboxamide derivative; 8β-Carboxamide ergoline derivative; 81409-86-1 (CAS Name-based synonym)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Each batch is characterized using advanced analytical techniques to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results from HPLC, NMR, and mass spectrometry are available upon request, providing full traceability and supporting your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.