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Rac Erythro-9-(2-Hydroxy-3-Nonyl)Adenine, Hydrochloride CAS NO 81408-49-3
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CAS No.:81408-49-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Rac Erythro-9-(2-Hydroxy-3-Nonyl)Adenine, Hydrochloride is a high-purity, small molecule inhibitor primarily used in biochemical and pharmacological research. This compound matters as a potent and selective adenosine deaminase inhibitor, enabling critical studies in purine metabolism, immunology, and cardiovascular function. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors who require reliable, well-characterized chemical tools for target validation and assay development.
Application
- Biochemical Research: As a key tool compound for studying adenosine deaminase (ADA) enzyme kinetics and inhibition mechanisms.
- Immunology Studies: Used to investigate the role of adenosine signaling in immune cell regulation and inflammatory responses.
- Cardiovascular Research: Applied in models to understand adenosine's effects on heart rate, vasodilation, and ischemic preconditioning.
- Pharmaceutical Development: Serves as a reference standard and starting material in the discovery of novel ADA-targeting therapeutics.
- Diagnostic Reagent Manufacturing: Incorporated into enzymatic assay kits for clinical and research diagnostics related to purine metabolism disorders.
- Cell Culture & In Vitro Studies: Utilized to modulate extracellular adenosine levels in cell-based assays and tissue culture experiments.
Basic Information
| Product Name | Rac Erythro-9-(2-Hydroxy-3-Nonyl)Adenine, Hydrochloride |
| CAS No. | 81408-49-3 |
| Molecular Formula | C₁₅H₂₄ClN₅O₂ |
| Molecular Weight | 341.83 g/mol |
| Synonyms | EHNA hydrochloride; Erythro-9-(2-Hydroxy-3-Nonyl)Adenine HCl; (±)-Erythro-9-(2-Hydroxy-3-Nonyl)adenine hydrochloride; ADA Inhibitor (EHNA); 9-(2-Hydroxy-3-nonyl)adenine hydrochloride (racemic erythro form); NSC 326223; Adenosine Deaminase Inhibitor I; BIA 1 |
| EINECS | Contact for details |
Quality Control
Our Rac Erythro-9-(2-Hydroxy-3-Nonyl)Adenine, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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