Description

19(R)-Hydroxy Prostaglandin F1Alpha is a specialized prostaglandin analog and a key intermediate in the synthesis of more complex bioactive molecules. This compound matters for its role in advanced pharmaceutical research and development, particularly in studies related to ocular pressure, smooth muscle activity, and inflammatory pathways. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing novel therapeutics and reference standards.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced prostaglandin-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in studies investigating prostaglandin receptors, signal transduction, and metabolic pathways.
• Ophthalmology Research: Serves as a precursor or analog in the development of novel intraocular pressure-lowering agents for glaucoma treatment.
• Cell Culture & In Vitro Studies: Applied in controlled laboratory environments to study its effects on cellular proliferation, inflammation, and smooth muscle contraction.
• Metabolite Standard: Utilized in analytical laboratories (e.g., LC-MS, HPLC) for the identification and quantification of prostaglandin metabolites in biological samples.

Basic Information

Product Name	19(R)-Hydroxy Prostaglandin F1Alpha
CAS No.	81371-59-7
Molecular Formula	C₂₀H₃₆O₆
Molecular Weight	372.50 g/mol
Synonyms	19(R)-Hydroxy PGF1α; (5Z,9α,11α,13E,15S,19R)-9,11,15,19-Tetrahydroxyprosta-5,13-dien-1-oic acid; 19R-Hydroxy Prostaglandin F1α; 19(R)-OH-PGF1α; Prostaglandin F1α 19(R)-isomer; 19(R)-Hydroxyprosta-5,13-dien-1-oic acid, 9,11,15,19-tetrahydroxy-, (5Z,9α,11α,13E,15S)-
EINECS	Contact for details

Quality Control

Our 19(R)-Hydroxy Prostaglandin F1Alpha is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, keep the primary container sealed within a secondary, light-proof barrier. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.