Description

5-Bromo-2-Chlorobenzene-1-Sulfonyl Chloride is a versatile and highly reactive organosulfur compound, primarily used as a key sulfonylation reagent and building block in advanced organic synthesis. Its value lies in its ability to introduce the sulfonyl chloride functional group, a crucial precursor for creating sulfonamides and other sulfonyl derivatives with diverse properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it facilitates the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in creating sulfonamide-based therapeutics which are prevalent in various drug classes.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the sulfonyl moiety can contribute to biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and colorants.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and labeling of biomolecules due to its sulfonyl chloride group's reactivity with amines and alcohols.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	5-Bromo-2-Chlorobenzene-1-Sulfonyl Chloride
CAS No.	81226-68-8
Molecular Formula	C6H3BrCl2O2S
Molecular Weight	289.96 g/mol
Synonyms	2-Chloro-5-Bromobenzenesulfonyl Chloride; 5-Bromo-2-Chlorobenzenesulfonyl Chloride; 1-Bromo-4-Chloro-3-(Chlorosulfonyl)benzene; Benzenesulfonyl chloride, 5-bromo-2-chloro-; 3-Bromo-6-Chlorobenzenesulfonyl Chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Chlorobenzene-1-Sulfonyl Chloride is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are issued with each shipment to guarantee traceability and support your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.