Description

L-Methionine-1-13C CAS NO 81202-04-2 is a stable isotope-labeled analog of the essential amino acid L-Methionine, where the carbon atom at the 1-position is enriched with the 13C isotope. This precise labeling is critical for applications requiring high sensitivity and accurate metabolic pathway tracing, such as in-vivo and in-vitro studies. It is an indispensable research tool for scientists and manufacturers in the fields of pharmaceutical development, nutritional research, and advanced biochemical analysis.

Application

• Metabolic Research & Tracer Studies: Used as an internal standard in mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy for quantitative analysis of methionine metabolism.
• Pharmaceutical Development: Employed in the research and development of new drugs, particularly in pharmacokinetic (PK) and pharmacodynamic (PD) studies to track drug absorption and metabolism.
• Nutritional Science: Serves as a tracer in studies investigating protein synthesis, amino acid utilization, and metabolic disorders related to methionine pathways.
• Biochemical Analysis: Acts as a critical standard for calibrating analytical instruments and validating methods in clinical and research laboratories.
• Isotope-Labeled Compound Synthesis: Used as a high-purity building block for the synthesis of more complex 13C-labeled peptides, proteins, or other bioactive molecules.

Basic Information

Product Name	L-Methionine-1-13C
CAS No.	81202-04-2
Molecular Formula	C413CH11NO2S
Molecular Weight	150.20 g/mol (for 13C1 labeled form)
Synonyms	(2S)-2-Amino-4-(methylsulfanyl)-1-13C-butanoic acid; L-2-Amino-4-(methylthio)-1-13C-butyric acid; (S)-2-Amino-4-(methylthio)-1-13C-butyric acid; L-Methionine-1-13C; [1-13C]-L-Methionine; L-Methionine (1-13C); Methionine-1-13C, L-; 13C Labeled L-Methionine
EINECS	Contact for details

Quality Control

Our L-Methionine-1-13C is manufactured under strict quality control protocols to ensure the highest isotopic and chemical purity for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (Atom % 13C), chemical purity (by HPLC), chiral purity, and residual solvent content. We adhere to cGMP guidelines for the production of reference standards and high-value biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % 13C)	≥ 99%
Chiral Purity ([α]D)	≥ 99.0% L-Isomer
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.