Description

L-Phenylalanine (1-13C) CAS NO 81201-86-7 is a stable isotope-labeled analog of the essential amino acid L-Phenylalanine, where the carbon at the 1-position is the carbon-13 isotope. This compound is critical for advanced research and development, providing a non-radioactive tracer for precise metabolic and pharmacokinetic studies. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and diagnostic manufacturers for applications in mass spectrometry, NMR spectroscopy, and clinical research.

Application

• Biomedical Research Tracer: Used as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate quantification of phenylalanine and related metabolites in biological samples.
• Metabolic Pathway Analysis: Enables the detailed tracing of phenylalanine metabolism in studies related to phenylketonuria (PKU), protein synthesis, and neurotransmitter production.
• Pharmaceutical Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the absorption, distribution, metabolism, and excretion of new drug candidates containing phenylalanine moieties.
• Nutritional Science Studies: Facilitates research into amino acid uptake, protein turnover, and the effects of dietary supplements in both clinical and animal model settings.
• Diagnostic Reagent Manufacturing: Serves as a key raw material in the production of calibrated assays and diagnostic kits for metabolic disorder testing.

Basic Information

Product Name	L-Phenylalanine (1-13C)
CAS No.	81201-86-7
Molecular Formula	C9H1113CNO2
Molecular Weight	166.19 g/mol (for 13C1 isotopologue)
Synonyms	(S)-2-Amino-3-phenylpropionic acid-1-13C; L-α-Amino-β-phenylpropionic acid-1-13C; L-Phe-1-13C; Phenylalanine-1-13C; F-1-13C; (S)-Phenylalanine-1-13C; (2S)-2-Azaniumyl-3-phenylpropanoate-1-13C; Isotope-labeled L-Phenylalanine
EINECS	Contact for details

Quality Control

Our L-Phenylalanine (1-13C) is manufactured under strict quality systems to ensure high isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and specific analytical results. We adhere to relevant industry standards for research-grade biochemicals, ensuring reliability and consistency for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific rotation conforms
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.