Description

Anhydro Vinblastine Disulfate Salt is a semi-synthetic derivative of the potent vinca alkaloid vinblastine, specifically modified to enhance its stability and pharmacological profile. This compound is of critical importance in advanced pharmaceutical research and development, particularly in the study of novel anti-mitotic and anti-cancer agents. It serves as a key intermediate and reference standard for researchers and manufacturers in the oncology and life science sectors, enabling the development of next-generation chemotherapeutic treatments and targeted drug delivery systems.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for quality control and analytical method development in drug manufacturing.
• Oncology Research: Serves as a critical biochemical tool and precursor in the research of microtubule dynamics, cell cycle inhibition, and apoptosis mechanisms.
• Drug Discovery & Development: Acts as a key intermediate in the synthesis and structural modification of novel vinca alkaloid derivatives with potential therapeutic applications.
• Biochemical Assays: Utilized in in vitro studies to investigate the potency, selectivity, and mechanism of action of anti-mitotic compounds.
• Academic & Institutional Research: Provides a reliable material for universities and research institutes studying cancer biology and medicinal chemistry.

Basic Information

Item	Detail
Product Name	Anhydro Vinblastine Disulfate Salt
CAS No.	81165-17-5
Molecular Formula	C46H58N4O9 • H2SO4
Molecular Weight	909.06 g/mol (for free base C46H58N4O9)
Synonyms	Anhydrovinblastine Disulfate; 3',4'-Didehydrovinblastine Disulfate; 3',4'-Anhydrovinblastine Disulfate; Leurosidine Disulfate; Vindesine Related Compound A (Disulfate); NSC 49842 (Disulfate); Catharanthus roseus Alkaloid Derivative
EINECS	Contact for details

Quality Control

Every batch of Anhydro Vinblastine Disulfate Salt is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.