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6-Oxo-9Alpha,11Alpha,15S-Trihydroxy-Prosta-13E,17Z-Dien-1-Oic Acid CAS NO 80779-61-9


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CAS No.:80779-61-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Oxo-9Alpha,11Alpha,15S-Trihydroxy-Prosta-13E,17Z-Dien-1-Oic Acid is a high-purity prostaglandin derivative and a key intermediate in the synthesis of advanced pharmaceutical compounds. Its precise stereochemistry and functional groups make it a critical building block for research and development in life sciences. This compound is essential for pharmaceutical manufacturers and research institutions focused on developing novel therapeutics, particularly in the areas of inflammation, immunology, and metabolic regulation.

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of prostaglandin-based active pharmaceutical ingredients (APIs) and drug candidates.
  • Biochemical Research: Used as a reference standard and a tool compound in pharmacological studies to investigate prostaglandin receptor activity and signaling pathways.
  • Drug Discovery: Serves as a scaffold for medicinal chemistry programs aimed at developing new anti-inflammatory, cardiovascular, or ophthalmic agents.
  • Analytical Standard: Employed in analytical method development and validation (e.g., HPLC, LC-MS) for quality control of prostaglandin-related products.
  • Academic Research: Utilized in university and institutional labs for fundamental studies in lipid biochemistry and cell biology.

Basic Information

Product Name 6-Oxo-9Alpha,11Alpha,15S-Trihydroxy-Prosta-13E,17Z-Dien-1-Oic Acid
CAS No. 80779-61-9
Molecular Formula C₂₀H₃₂O₆
Molecular Weight 368.47 g/mol
Synonyms 9α,11α,15S-Trihydroxy-6-oxoprosta-13E,17Z-dien-1-oic Acid; 6-Keto-PGF1α; 6-Ketoprostaglandin F1α; 6-Oxo-PGF1α; 6-Oxo-prostaglandin F1α; 9,11,15-Trihydroxy-6-oxoprosta-13,17-dienoic Acid; PGI2 Metabolite; 6-Keto Prostaglandin F1α
EINECS Contact for details

Quality Control

Our 6-Oxo-9Alpha,11Alpha,15S-Trihydroxy-Prosta-13E,17Z-Dien-1-Oic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Any single impurity ≤ 1.0%
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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