Description

Skf 83959 Hydrobromide is a selective dopamine receptor antagonist and a potent research chemical. This compound is of significant value for its role in neuropharmacological studies, particularly in investigating dopamine D1-like receptor signaling pathways and related neurological functions. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and academic researchers focused on neuroscience, psychopharmacology, and drug discovery.

Application

• Neuroscience Research: A key tool for studying dopamine D1 receptor-mediated behaviors and signal transduction mechanisms.
• Pharmacological Profiling: Used in in vitro and in vivo assays to characterize receptor selectivity and functional activity.
• Psychiatric Disorder Models: Employed in preclinical research to explore the pathophysiology and potential treatments for disorders like schizophrenia and Parkinson's disease.
• Biochemical Assay Standard: Serves as a reference standard in high-throughput screening (HTS) and biochemical testing.
• Academic & Institutional R&D: Fundamental for university and institutional research programs in neurochemistry and molecular pharmacology.

Basic Information

Product Name	Skf 83959 Hydrobromide
CAS No.	80751-85-5
Molecular Formula	C17H19BrN2O2 • HBr
Molecular Weight	428.17 g/mol
Synonyms	SKF-83959 HBr; 6-Chloro-7,8-dihydroxy-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide; 6-Chloro-7,8-dihydroxy-3-methyl-1-(m-tolyl)-2,3,4,5-tetrahydro-1H-3-benzazepine HBr; SKF 83959; Benzazepine, SKF-83959; Dopamine D1 antagonist SKF-83959; Research compound SKF83959.
EINECS	Contact for details

Quality Control

Our Skf 83959 Hydrobromide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.