Description

Somatotropin (135-191) CAS NO 80738-38-1 is a bioactive fragment of human growth hormone, representing a key sequence for research into receptor binding and biological activity. This high-purity peptide is critical for advancing scientific understanding in endocrinology and developing novel therapeutic approaches. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on metabolic disorders, growth deficiencies, and peptide-based drug discovery.

Application

• Biochemical Research: Used as a standard and reagent in studies investigating the structure-activity relationship (SAR) of growth hormone.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the R&D of novel growth hormone analogs and mimetics.
• Receptor Binding Studies: Essential for in vitro assays to characterize and quantify the interaction between growth hormone and its receptor (GHR).
• Cell Culture & Bioassays: Employed to stimulate cellular pathways and study downstream effects in relevant cell lines.
• Antibody Production: Can be used as an immunogen to generate specific antibodies for diagnostic or research immunoassays.
• Academic Research: Fundamental tool for university labs studying endocrinology, peptide chemistry, and molecular biology.

Basic Information

Product Name	Somatotropin (135-191)
CAS No.	80738-38-1
Molecular Formula	C254H402N72O73S2
Molecular Weight	~5749.5 g/mol
Synonyms	Human Growth Hormone Fragment (135-191); hGH (135-191); Somatropin (135-191); GH (135-191); Growth Hormone (135-191); Somatotrophin (135-191); Pituitary Growth Hormone Fragment; Recombinant hGH Fragment 135-191
EINECS	Contact for details

Quality Control

Our Somatotropin (135-191) is manufactured under stringent conditions to ensure the highest standards of purity and consistency. Each batch is subjected to a comprehensive battery of analytical tests, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Single Impurity (HPLC)	≤ 2.0%
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.