Description

Methisosildenafil CAS NO 80540-58-5 is a high-purity pharmaceutical intermediate and research chemical. It serves as a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. This compound is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of specialized active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and new drug candidate development.
• Reference Standard: Serves as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Employed in pharmacological studies to investigate specific enzyme interactions and biological mechanisms.
• Fine Chemical Synthesis: A valuable building block for creating complex, high-value organic molecules in contract manufacturing.

Basic Information

Product Name	Methisosildenafil
CAS No.	80540-58-5
Molecular Formula	C22H30N6O4S
Molecular Weight	474.58 g/mol
Synonyms	Methylisosildenafil; 5-[2-Ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one; Thioaildenafil; Methisosildenafil citrate (salt form); Methisosildenafil hydrochloride (salt form); Methisosildenafil base
EINECS	Contact for details

Quality Control

Our Methisosildenafil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation via spectroscopic methods (IR, NMR, MS). We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.