Description

6-Fluoro-1,2,3,4-Tetrahydro-2-Methylquinolinium Chloride is a high-purity, advanced pharmaceutical intermediate and building block of significant synthetic utility. This compound is valued for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is primarily sought by research institutions, custom synthesis firms, and pharmaceutical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of complex drug candidates, especially those with quinoline-based structures.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for active pharmaceutical ingredients (APIs).
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule synthesis.
• Chemical Reference Standard: Can be utilized as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	6-Fluoro-1,2,3,4-Tetrahydro-2-Methylquinolinium Chloride
CAS No.	80518-48-5
Molecular Formula	C₁₀H₁₃ClFN
Molecular Weight	201.67 g/mol
Synonyms	2-Methyl-6-fluoro-1,2,3,4-tetrahydroquinolinium chloride; 6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinolinium chloride; 1,2,3,4-Tetrahydro-6-fluoro-2-methylquinolinium chloride; 2-Methyl-6-fluorotetrahydroquinolinium chloride; 6-Fluoro-2-methyl-3,4-dihydro-1H-quinolinium chloride; Quinolinium, 1,2,3,4-tetrahydro-6-fluoro-2-methyl-, chloride (1:1)
EINECS	Contact for details

Quality Control

Our 6-Fluoro-1,2,3,4-Tetrahydro-2-Methylquinolinium Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.