Description

2,4-Dimethyl-1,3-thiazole-5-sulfonyl chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the 2,4-dimethylthiazole-5-sulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional intermediates. Its specific reactivity profile makes it a key material for developing compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs and molecules requiring a thiazole heterocycle.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the thiazole-sulfonyl group can confer specific biological properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling, modifying, or cross-linking biomolecules such as proteins and peptides in research applications.
• Material Science: Can be utilized in the synthesis of specialty polymers, dyes, or functional materials that incorporate sulfur and nitrogen heterocycles for specific electronic or physical characteristics.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom chemical synthesis services, enabling the production of tailored compounds for client-specific R&D projects.

Basic Information

Product Name	2,4-Dimethyl-1,3-thiazole-5-sulfonyl chloride
CAS No.	80466-80-4
Molecular Formula	C5H6ClNO2S2
Molecular Weight	211.69 g/mol
Synonyms	2,4-Dimethylthiazole-5-sulfonyl chloride; 5-(Chlorosulfonyl)-2,4-dimethylthiazole; 2,4-Dimethyl-5-thiazolesulfonyl chloride; 1,3-Thiazole-5-sulfonyl chloride, 2,4-dimethyl-; 5-Chlorosulfonyl-2,4-dimethylthiazole
EINECS	Contact for details

Quality Control

Our 2,4-Dimethyl-1,3-thiazole-5-sulfonyl chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets high-purity standards suitable for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.