Description

3,5-Dimethylisoxazole-4-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, primarily used as a key synthetic intermediate in organic chemistry. Its core value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the sulfonyl functional group into target molecules, which is crucial for modifying physicochemical properties and biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs), specialty chemicals, and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the sulfonyl moiety imparts specific biological activity.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial R&D labs for constructing complex heterocyclic scaffolds and functional materials.
• Sulfonamide Library Production: Enables high-throughput synthesis of diverse sulfonamide compounds for screening in drug discovery programs.
• Specialty Chemical Manufacturing: Employed in the production of dyes, pigments, and performance chemicals requiring sulfonyl group incorporation.

Basic Information

Item	Details
Product Name	3,5-Dimethylisoxazole-4-Sulfonyl Chloride
CAS No.	80466-79-1
Molecular Formula	C5H6ClNO3S
Molecular Weight	195.62 g/mol
Synonyms	4-Chlorosulfonyl-3,5-dimethylisoxazole; 3,5-Dimethyl-4-isoxazolesulfonyl chloride; 3,5-Dimethylisoxazole-4-sulfonyl chloride; 3,5-Dimethyl-1,2-oxazole-4-sulfonyl chloride; Isoxazole-4-sulfonyl chloride, 3,5-dimethyl-; 4-(Chlorosulfonyl)-3,5-dimethylisoxazole
EINECS	Contact for details

Quality Control

Our 3,5-Dimethylisoxazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.