Description

Ethanone, 2-Fluoro-1-(2-Pyridinyl)- (9Ci) CAS NO 80458-99-7 is a high-purity fluorinated pyridinyl ketone building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a key strategy for modulating biological activity and metabolic stability. It is essential for research chemists and process development scientists working on novel active ingredients, including kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorination enhances efficacy and environmental profile.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies.
• Ligand and Catalyst Precursor: Potential use in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Applications: Exploration in the synthesis of fluorinated organic electronic materials and specialty polymers.

Basic Information

Product Name	Ethanone, 2-Fluoro-1-(2-Pyridinyl)- (9Ci)
CAS No.	80458-99-7
Molecular Formula	C7H6FNO
Molecular Weight	139.13 g/mol
Synonyms	2-Fluoro-1-(2-pyridinyl)ethanone; 2-Fluoro-1-(pyridin-2-yl)ethan-1-one; 2-Acetylpyridine, 2'-fluoro-; 2-Fluoro-2-pyridyl methyl ketone; 2-Pyridyl 2-fluoroethyl ketone; 1-(2-Pyridinyl)-2-fluoroethanone; 2-Fluoro-1-(2-pyridyl)ethanone
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Fluoro-1-(2-Pyridinyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali conditions; ensure storage areas are free from such incompatible materials. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.