Description

4-Oxo-2,2,6,6-Tetramethylpiperidine (D17, 15N) is a high-purity, isotopically labeled derivative of the TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl) precursor, specifically enriched with deuterium and nitrogen-15. This compound is essential for advanced research and analytical applications where precise molecular tracking and quantification are required. It is primarily utilized by scientists and manufacturers in the fields of pharmaceutical development, NMR spectroscopy, and metabolic research.

Application

• NMR Spectroscopy: Serves as a crucial internal standard or reference compound for quantitative nuclear magnetic resonance (qNMR) due to its stable isotopic labeling (D17, 15N).
• Pharmaceutical Research: Used as a labeled intermediate in the synthesis of deuterated drug candidates for pharmacokinetic and metabolic stability studies.
• Metabolic Pathway Tracing: Acts as a probe in mass spectrometry and isotopic labeling experiments to study biochemical pathways and mechanisms.
• Polymer Chemistry: Functions as a precursor for labeled nitroxide mediators in controlled radical polymerization processes for advanced material science.
• Analytical Reference Standards: Provides a high-purity certified reference material (CRM) for calibrating analytical instruments and validating methods in regulatory environments.
• Spin Labeling: Employed in electron paramagnetic resonance (EPR) spectroscopy for investigating protein dynamics and macromolecular structures.

Basic Information

Product Name	4-Oxo-2,2,6,6-Tetramethylpiperidine (D17, 15N)
CAS No.	80404-11-1
Molecular Formula	C9D1715NO
Molecular Weight	Contact for details
Synonyms	2,2,6,6-Tetramethyl-4-piperidone-d17-15N; 4-Oxo-TEMPO-d17-15N precursor; 2,2,6,6-Tetramethyl-4-oxopiperidine-d17 (15N); TAA-d17-15N; Triacetonamine-d17-15N; 4-Keto-2,2,6,6-tetramethylpiperidine-d17-15N; 4-Oxo-TMP-d17-15N; Deutero-Nitrogen-15 labeled 4-oxo-TEMPO precursor
EINECS	Contact for details

Quality Control

Our isotopically labeled chemicals are produced and tested under stringent conditions to ensure exceptional isotopic and chemical purity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (D and 15N), chemical purity by HPLC, and identity confirmation. We adhere to cGMP and ISO 9001 quality management principles for traceability and consistency, catering to the rigorous demands of research and regulatory submission.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (D)	≥ 98 atom % D
Nitrogen-15 Enrichment (15N)	≥ 98 atom % 15N
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.