Description

Quinpirole is a selective dopamine D2 and D3 receptor agonist, a high-purity chemical compound essential for advanced neuroscience and pharmacological research. Its specific receptor activity makes it a critical tool for studying dopaminergic pathways, neurological disorders, and potential therapeutic targets. This compound is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and contract research organizations (CROs) focused on central nervous system drug discovery and development.

Application

• Neuroscience Research: A key pharmacological tool for investigating the function and modulation of dopamine D2 and D3 receptors in the brain.
• Behavioral Pharmacology Studies: Used in animal models to study locomotor activity, reward mechanisms, and stereotypic behaviors linked to dopaminergic systems.
• Drug Discovery & Development: Serves as a reference standard and active compound in screening assays for novel antipsychotic, anti-Parkinson's, and anti-addiction therapies.
• Biochemical Assays: Employed in in vitro receptor binding and functional assays (e.g., cAMP accumulation) to characterize drug-receptor interactions.
• Academic & Institutional Research: Fundamental for university and hospital labs conducting basic research on neurotransmission, neuropsychiatric conditions, and signal transduction.

Basic Information

Product Name	Quinpirole
CAS No.	80373-22-4
Molecular Formula	C16H24N2O
Molecular Weight	260.38 g/mol
Synonyms	Quinpirole Hydrochloride (common salt form); LY-171555; trans-(-)-4aR,8aR-4,4a,5,6,7,8,8a,9-Octahydro-5-propyl-1H-pyrazolo[3,4-g]quinoline; (-)-Quinpirole; Quinpirol; PD-128,907 (related D3-preferring agonist)
EINECS	Contact for details

Quality Control

We supply Quinpirole in high-purity grades suitable for research applications. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by validated analytical methods (e.g., HPLC, NMR) is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.