Description

1,2-Dichloro-5-Methyl-3-Trifluoromethyl-Benzene is a high-purity halogenated aromatic building block of significant commercial importance. This compound serves as a critical intermediate in the synthesis of advanced agrochemicals and pharmaceuticals, where its unique substitution pattern enables the construction of complex, bioactive molecules. It is primarily sought after by research institutions and industrial manufacturers in the fine chemical and life science sectors for developing new active ingredients.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the stability and reactivity of the trifluoromethyl and chloro substituents.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing fluorinated aromatic cores which can enhance metabolic stability and bioavailability.
• Material Science Research: Employed as a monomer or building block for developing specialty polymers, liquid crystals, and advanced organic electronic materials.
• Dye and Pigment Synthesis: Serves as a starting material for creating complex, halogenated dyes and pigments with specific light-fastness and color properties.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) due to the presence of reactive chlorine atoms.
• Custom Synthesis and R&D: Utilized by contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects and process development.

Basic Information

Item	Detail
Product Name	1,2-Dichloro-5-Methyl-3-Trifluoromethyl-Benzene
CAS No.	80245-33-6
Molecular Formula	C8H5Cl2F3
Molecular Weight	229.03 g/mol
Synonyms	2,3-Dichloro-6-(trifluoromethyl)toluene; 3,4-Dichloro-α,α,α-trifluoro-o-xylene; 1,2-Dichloro-5-methyl-3-(trifluoromethyl)benzene; 2,3-Dichloro-α,α,α-trifluoro-6-methyltoluene; 3-Trifluoromethyl-1,2-dichloro-5-methylbenzene; 5-Methyl-1,2-dichloro-3-trifluoromethylbenzene; Benzene, 1,2-dichloro-5-methyl-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 1,2-Dichloro-5-Methyl-3-Trifluoromethyl-Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. Ensure the container is kept upright to prevent leakage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.