Description

2-Chloro-5-Methylbenzotrifluoride is a versatile halogenated aromatic building block characterized by its trifluoromethyl and chloro substituents, which impart unique electronic and steric properties. This compound is essential for facilitating advanced synthesis in fine chemical and pharmaceutical research, offering a reliable pathway to complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for constructing active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the stability and reactivity of the benzotrifluoride core.
• Pharmaceutical Building Block: Used in medicinal chemistry for the construction of drug candidates, particularly those requiring the metabolically stable trifluoromethyl group.
• Liquid Crystal & OLED Material Synthesis: Serves as a starting material for creating fluorinated aromatic components used in electronic display technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of high-performance, light-fast fluorinated dyes and pigments.
• Cross-Coupling Reactions: An effective substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions for carbon-carbon bond formation.

Basic Information

Product Name	2-Chloro-5-Methylbenzotrifluoride
CAS No.	80245-27-8
Molecular Formula	C8H6ClF3
Molecular Weight	194.58 g/mol
Synonyms	1-Chloro-2-methyl-4-(trifluoromethyl)benzene; 2-Chloro-α,α,α-trifluoro-p-xylene; 4-Chloro-3-methylbenzotrifluoride; 2-Chloro-5-methyl-α,α,α-trifluorotoluene; 5-Methyl-2-chlorobenzotrifluoride; 2-Chloro-5-(trifluoromethyl)toluene; 3-Methyl-4-chlorobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Methylbenzotrifluoride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials such as strong acids and organic solvents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature: 15-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.35 g/cm³
Refractive Index (n20D)	~1.45

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.