Description

4-Fluoro-2-Methylbenzotrifluoride is a versatile fluorinated aromatic building block of significant commercial importance. Its unique structure, featuring both a fluorine atom and a trifluoromethyl group on a methylbenzene core, makes it a critical intermediate in advanced chemical synthesis. This compound is primarily sought after by the pharmaceutical and agrochemical industries for the development of novel active ingredients, as well as by material scientists for creating specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups contribute to efficacy and environmental persistence profiles.
• Liquid Crystal Materials: Serves as a fundamental building block for fluorinated liquid crystal compounds used in display technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter properties such as chemical resistance, thermal stability, and dielectric characteristics.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a precursor for further functionalization in complex molecule construction.
• Research & Development: Utilized in academic and industrial R&D settings for exploring new chemical entities and reaction pathways involving fluorinated aromatics.

Basic Information

Product Name	4-Fluoro-2-Methylbenzotrifluoride
CAS No.	80245-26-7
Molecular Formula	C9H6F4
Molecular Weight	190.14 g/mol
Synonyms	1-Fluoro-2-methyl-4-(trifluoromethyl)benzene; 2-Methyl-4-(trifluoromethyl)fluorobenzene; 4-Fluoro-α,α,α-trifluoro-o-xylene; 4-Fluoro-2-methylbenzotrifluoride; 2-Methyl-α,α,α,4-tetrafluorotoluene; 4-(Trifluoromethyl)-2-fluorotoluene; 2-Fluoro-5-methylbenzotrifluoride (isomer reference); F-2-MBTF
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methylbenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent quality suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.30 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.