Description

5-Acetonyl-2-Methoxybenzenesulphonylchloride is a specialized organic sulfonyl chloride derivative, serving as a critical building block in advanced chemical synthesis. Its reactive sulfonyl chloride group makes it an essential intermediate for constructing complex molecules with sulfonamide linkages. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides where the sulfonamide moiety is required for biological activity.
• Organic Synthesis Reagent: Acts as a versatile electrophile for introducing the methoxybenzenesulfonyl group into target molecules in research-scale and process chemistry.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized sulfonated dyes and colorants.
• Material Science Research: Building block for creating monomers or additives for advanced polymers and functional materials.

Basic Information

Product Name	5-Acetonyl-2-Methoxybenzenesulphonylchloride
CAS No.	80223-79-6
Molecular Formula	C10H11ClO4S
Molecular Weight	262.71 g/mol
Synonyms	1-(4-Methoxy-3-sulfonylchloridophenyl)-2-propanone; 2-Methoxy-5-acetonylbenzenesulfonyl chloride; 3-Acetonyl-6-methoxybenzenesulfonyl chloride; 4-Methoxy-3-(2-oxopropyl)benzenesulfonyl chloride; 5-Acetonyl-2-methoxybenzenesulfonyl chloride; 5-Acetonyl-2-methoxybenzene-1-sulfonyl chloride; 5-(2-Oxopropyl)-2-methoxybenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Acetonyl-2-Methoxybenzenesulphonylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.