Description

3,4,5-Trifluorobenzotrifluoride is a high-value fluorinated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring both a trifluoromethyl group and a trifluorinated benzene ring, makes it a critical intermediate for introducing fluorine atoms into complex molecules. This compound is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for developing novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where fluorine substitution improves efficacy and environmental profile.
• Liquid Crystal Materials (LCM): Serves as a core component in the synthesis of fluorinated liquid crystals for high-performance displays.
• Organic Electronics: Intermediate for creating electron-transport materials and semiconductors in OLEDs and organic photovoltaics.
• Specialty Polymers: Monomer for engineering plastics and coatings that require high thermal stability, chemical resistance, and low dielectric constant.
• Fluorinated Dyes and Pigments: Imparts light-fastness and chemical stability to high-value colorants.

Basic Information

Product Name	3,4,5-Trifluorobenzotrifluoride
CAS No.	80172-04-9
Molecular Formula	C7H2F6
Molecular Weight	200.08 g/mol
Synonyms	1,2,3-Trifluoro-5-(trifluoromethyl)benzene; 3,4,5-Trifluoro-α,α,α-trifluorotoluene; 3,4,5-Trifluorobenzylidene trifluoride; α,α,α,3,4,5-Hexafluorotoluene; Benzene, 1,2,3-trifluoro-5-(trifluoromethyl)-; 5-(Trifluoromethyl)-1,2,3-trifluorobenzene; TFB-TF; Hexafluorotoluene, 3,4,5-trifluoro- derivative
EINECS	Contact for details

Quality Control

Our 3,4,5-Trifluorobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our production adheres to cGMP and ISO 9001 standards where applicable, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	~1.55 g/cm³
Boiling Point	~145-147 °C
Refractive Index (n20D)	~1.395

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.