Description

(15S)-15-Methyl-Prostaglandin F2-Alpha 1,11-Lactone CAS NO 80029-28-3 is a synthetic analog of prostaglandin F2α, featuring a 15-methyl substitution and a stable 1,11-lactone ring. This structural modification enhances its metabolic stability and biological activity profile, making it a valuable intermediate for advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for developing novel therapeutic agents, particularly in the fields of ophthalmology and reproductive health.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced prostaglandin-based drugs.
• Ophthalmic Research: Used in the development of novel treatments for glaucoma and ocular hypertension.
• Reproductive Health Studies: Serves as a reference standard and active component in fertility and parturition research.
• Biochemical Tool Compound: Employed in vitro to study FP receptor signaling pathways and cellular responses.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for prostaglandin analogs.
• Reference Standard: Provides a high-purity benchmark for analytical method development and quality control in API manufacturing.

Basic Information

Item	Detail
Product Name	(15S)-15-Methyl-Prostaglandin F2-Alpha 1,11-Lactone
CAS No.	80029-28-3
Molecular Formula	C₂₁H₃₂O₄
Molecular Weight	348.48 g/mol
Synonyms	15(S)-15-Methyl-PGF2α 1,11-Lactone; 15-Methylprostaglandin F2α 1,11-Lactone; 9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid 1,11-lactone; Travoprost Related Compound C; Travoprost Impurity C; AL-6221 Lactone; 15-Methyl-PGF2α Lactone; (15S)-15-Methyl-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid γ-lactone
EINECS	Contact for details

Quality Control

Our (15S)-15-Methyl-Prostaglandin F2-Alpha 1,11-Lactone is manufactured under strict quality systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. Keep the container in a dry, well-ventilated area. Handle and store under an inert atmosphere if the container is opened repeatedly to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.