Description

2-Cyano-3-Fluorobenzene-1-Sulfonyl Chloride is a high-value, multi-functional chemical building block essential for advanced organic synthesis. Its core value lies in the reactive sulfonyl chloride and nitrile groups, which enable precise derivatization for creating complex molecular architectures. This compound is critically needed by R&D and process development chemists in the pharmaceutical, agrochemical, and specialty materials industries for synthesizing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Used in the creation of specialty polymers, liquid crystals, and advanced electronic materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for activity-based protein profiling (ABPP) and bioconjugation strategies.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for bespoke chemical synthesis services for research and pilot-scale production.
• Dye & Pigment Industry: Intermediate for synthesizing specialized fluorinated dyes and colorants.

Basic Information

Product Name	2-Cyano-3-Fluorobenzene-1-Sulfonyl Chloride
CAS No.	80023-23-0
Molecular Formula	C7H3ClFNO2S
Molecular Weight	219.62 g/mol
Synonyms	3-Fluoro-2-cyanobenzenesulfonyl chloride; 2-Fluoro-6-cyanobenzenesulfonyl chloride; 2-Cyano-3-fluorobenzenesulfonyl chloride; 3-Fluoro-2-cyanobenzene-1-sulfonyl chloride; 2-Fluoro-6-(cyano)benzenesulfonyl chloride; 1-(Chlorosulfonyl)-2-fluoro-3-cyanobenzene; 80023-23-0; Benzenesulfonyl chloride, 2-cyano-3-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Cyano-3-Fluorobenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance for critical synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 15-25°C. This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.