Description

17,17-Dimethylprostaglandin E2 is a synthetic analog of the naturally occurring prostaglandin E2, distinguished by its dimethyl substitution at the 17-position. This structural modification enhances its metabolic stability and biological activity, making it a valuable tool compound in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for investigating inflammatory pathways, reproductive biology, and cellular signaling mechanisms.

Application

• Pharmaceutical Research & Development: A key intermediate and reference standard in the synthesis and study of novel anti-inflammatory and cytoprotective agents.
• Biochemical Research: Used as a potent agonist for studying prostaglandin receptors (EP receptors) and their role in various physiological and pathological processes.
• Cell Culture & In Vitro Studies: Employed to investigate its effects on smooth muscle contraction, vascular tone, and immune cell function in controlled laboratory settings.
• Standards & Calibration: Serves as a high-purity analytical standard for method development and quality control in analytical laboratories.

Basic Information

Product Name	17,17-Dimethylprostaglandin E2
CAS No.	80003-50-5
Molecular Formula	C22H36O5
Molecular Weight	380.52 g/mol
Synonyms	17,17-Dimethyl PGE2; 17,17-Dimethylprostaglandin E2; 11α,15α-Dihydroxy-17,17-dimethyl-9-oxoprosta-5,13-dien-1-oic acid; 17,17-Dimethyl-PGE2; DM-PGE2; 17,17-Dimethyl Prostaglandin E2; 17,17-Dimethyl-prostaglandin E2
EINECS	Contact for details

Quality Control

Our 17,17-Dimethylprostaglandin E2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. The product is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.