Description

Podophyllum Resin is a complex, standardized botanical extract derived from the roots of the *Podophyllum peltatum* (Mayapple) plant. This natural resin is a critical precursor in the pharmaceutical industry for the semi-synthesis of potent anticancer and antiviral agents. It serves as an essential raw material for manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring a reliable source of podophyllotoxin and related lignans.

Application

• Pharmaceutical Intermediates: Primary use as the starting material for the semi-synthesis of chemotherapeutic drugs such as etoposide, teniposide, and etopophos.
• Topical Formulations: Used in prescription dermatological preparations for the treatment of genital warts (condylomata acuminata) and other benign epithelial growths.
• Biomedical Research: Serves as a reference standard and active compound in pharmacological studies targeting topoisomerase II inhibition and apoptosis.
• Fine Chemical Synthesis: A key chiral building block for the synthesis of complex molecules in medicinal chemistry and drug discovery programs.
• Traditional Medicine: Basis for standardized extracts used in certain traditional and herbal medicinal preparations, under strict quality control.

Basic Information

Product Name	Podophyllum Resin
CAS No.	8050-60-0
Molecular Formula	Complex Mixture (Primarily C22H22O8 and related lignans)
Molecular Weight	414.41 g/mol (for Podophyllotoxin)
Synonyms	Podophyllin; Podophyllum Resin; Mayapple Resin; Podofilox; Mandrake Resin; American Podophyllum Resin; Indian Podophyllum Resin; Condylox (as a derivative)
EINECS	232-485-0

Quality Control

Our Podophyllum Resin is produced and tested to meet stringent pharmacopeial standards. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as podophyllotoxin content, identity, and purity. We adhere to cGMP guidelines where applicable, ensuring traceability and consistency for critical pharmaceutical applications. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Description	Brownish-green to yellow amorphous powder
Identification (IR)	Conforms to standard
Assay (Podophyllotoxin, HPLC)	Contact for details
Loss on Drying	≤ 5.0 %
Residue on Ignition	≤ 1.0 %
Heavy Metals	≤ 20 ppm
Microbiological Limits	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.