Description

4-Deoxypyridoxine 5-Phosphate is a phosphorylated derivative of 4-deoxypyridoxine, a structural analog and potent antagonist of vitamin B6 (pyridoxine). This compound matters as a critical biochemical tool for studying vitamin B6-dependent enzymatic pathways, particularly in the context of metabolic regulation and enzyme inhibition. It is primarily needed by researchers and manufacturers in the life sciences sector for applications in biochemical research, pharmaceutical development, and as a reference standard in analytical laboratories.

Application

• Biochemical Research: Used as a specific inhibitor to study the role of pyridoxal phosphate (PLP)-dependent enzymes in metabolic pathways.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the development of novel therapeutic agents targeting vitamin B6 metabolism.
• Enzymology Studies: Essential for investigating enzyme kinetics, mechanism of action, and inhibition profiles of PLP-dependent enzymes like transaminases and decarboxylases.
• Nutritional Science Research: Employed in studies exploring vitamin B6 deficiency, antagonism, and its physiological consequences.
• Analytical Reference Standard: Used for method development, calibration, and quality control in HPLC, LC-MS, and other analytical techniques within quality control laboratories.
• Cell Culture & Microbiology: Applied in defined media to create controlled B6-deficient conditions for studying cellular growth and metabolism.

Basic Information

Product Name	4-Deoxypyridoxine 5-Phosphate
CAS No.	883-84-1
Molecular Formula	C8H12NO6P
Molecular Weight	249.16 g/mol
Synonyms	4-Deoxypyridoxine 5'-Phosphate; 4-Deoxypyridoxine Phosphate; 5'-O-Phosphono-4-deoxypyridoxine; 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinic acid 4-phosphate; Pyridoxine antagonist phosphate; Vitamin B6 antagonist phosphate; 4-DP-5-P
EINECS	Contact for details

Quality Control

Our 4-Deoxypyridoxine 5-Phosphate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via techniques such as HPLC, NMR, and mass spectrometry is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.