Description

Trifluoromethylglyoxal-Bis(Guanylhydrazone) is a specialized guanylhydrazone derivative of significant interest in advanced chemical synthesis and pharmaceutical research. This compound serves as a critical building block and a potent inhibitor of specific enzymatic pathways, offering unique reactivity due to its trifluoromethyl and bis-guanylhydrazone functional groups. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and exploring new therapeutic modalities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition and metabolic pathways.
• Biochemical Research: Used as a potent and selective inhibitor of S-adenosylmethionine decarboxylase (AdoMetDC), a critical enzyme in polyamine biosynthesis, for cellular and molecular biology studies.
• Antiproliferative Agent Development: Investigated for its role in creating compounds with potential anticancer and antiparasitic properties due to its interference with polyamine metabolism.
• Agrochemical Synthesis: Serves as a high-value intermediate in the development of advanced crop protection agents with novel modes of action.
• Fine Chemical Synthesis: Employed in complex organic synthesis for introducing the trifluoromethylglyoxal-bis(guanylhydrazone) moiety into target molecules.

Basic Information

Product Name	Trifluoromethylglyoxal-Bis(Guanylhydrazone)
CAS No.	869-17-0
Molecular Formula	C6H10F3N7O
Molecular Weight	253.19 g/mol
Synonyms	Trifluoromethylglyoxal Bis(guanylhydrazone); 1,1'-[1,2-Bis(2-amino-1,2-dihydro-2-imino-1,4,5,6-tetrahydro-6-oxopyrimidin-5-yl)-2,2,2-trifluoroethylidene]diguanidine; NSC 32946; AdoMetDC Inhibitor; TFG-BG; Trifluoromethylglyoxal bisguanylhydrazone; 2,2,2-Trifluoro-1,2-bis[(aminoiminomethyl)hydrazono]ethane
EINECS	Contact for details

Quality Control

Our Trifluoromethylglyoxal-Bis(Guanylhydrazone) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.