Description

Lincomycin Hydrochloride is a lincosamide antibiotic derived from *Streptomyces lincolnensis*. This compound is valued for its potent activity against Gram-positive bacteria, particularly anaerobic organisms. It is a critical active pharmaceutical ingredient (API) for the formulation of injectable and topical pharmaceutical products in the human and veterinary sectors. Global B2B buyers rely on consistent, high-purity supplies to ensure the efficacy and safety of their final drug formulations.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in human injectable antibiotic formulations.
• Key component in veterinary pharmaceuticals for treating bacterial infections in livestock and companion animals.
• Manufacturing of topical creams, ointments, and gels for skin and soft tissue infections.
• Research and development of new antibiotic combinations and drug delivery systems.
• Reference standard material for quality control and analytical testing in pharmaceutical laboratories.
• Intermediate in the synthesis of more complex lincosamide antibiotic derivatives.

Basic Information

Product Name	Lincomycin Hydrochloride
CAS No.	859-18-7
Molecular Formula	C18H34N2O6S·HCl
Molecular Weight	461.01 g/mol
Synonyms	Lincomycin HCl; Lincomycin Monohydrochloride; Lincocin Hydrochloride; U-10149A; Lincolnensin; Cillinicina; Linco-Sol; (2S,4R)-N-[(1R,2R)-2-Hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide; Hydrochloride
EINECS	212-722-6

Quality Control

Our Lincomycin Hydrochloride is manufactured under strict quality management systems. Each batch is tested to meet or exceed relevant pharmacopeial standards, including USP and EP monographs where applicable. Comprehensive testing includes identity, purity, assay, and specific impurity profiling. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (1% solution)	3.0 - 5.5
Water (KF Titration)	NMT 6.0%
Residue on Ignition	NMT 0.5%
Related Substances (HPLC)	Total impurities NMT 2.0% Any individual impurity NMT 1.0%
Specific Rotation	+137° to +145° (c = 1 in water)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.