Description

Pentafluorobenzenesulfonyl Chloride is a highly reactive and versatile fluorinated aromatic building block essential for advanced organic synthesis. Its core value lies in its ability to act as a robust sulfonylation and fluorination agent, introducing the unique properties of pentafluorophenyl groups into target molecules. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of sulfonamide-based drugs, protease inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Building block for synthesizing specialty polymers, liquid crystals, and fluorinated surface modifiers.
• Peptide Chemistry: Employed as a coupling agent or protecting group reagent in solid-phase peptide synthesis (SPPS).
• Chemical Derivatization: Useful for analytical chemistry applications, such as derivatizing compounds for GC/MS or LC/MS analysis.
• Catalyst & Ligand Development: Serves as a precursor for creating novel organocatalysts and metal-organic frameworks (MOFs).

Basic Information

Product Name	Pentafluorobenzenesulfonyl Chloride
CAS No.	832-53-1
Molecular Formula	C6F5SO2Cl
Molecular Weight	262.57 g/mol
Synonyms	Pentafluorophenylsulfonyl chloride; Perfluorobenzenesulfonyl chloride; 2,3,4,5,6-Pentafluorobenzenesulfonyl chloride; Benzenesulfonyl chloride, pentafluoro-; C6F5SO2Cl; PFBS-Cl
EINECS	212-618-4

Quality Control

Our Pentafluorobenzenesulfonyl Chloride is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.