Description

(-)-3,4-Dihydroxynorephedrine is a chiral catecholamine derivative of significant interest in pharmaceutical and biochemical research. This compound serves as a key intermediate and reference standard in the development of adrenergic agents and neurological research tools. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroscience, cardiovascular studies, and synthetic organic chemistry. The product is supplied with a focus on high purity and batch-to-batch consistency to ensure reliable experimental results.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel adrenergic receptor agonists and antagonists.
• Biochemical Research: Used as a reference standard in studies of catecholamine metabolism, uptake, and receptor binding assays.
• Neuroscience Studies: Employed in research focusing on the sympathetic nervous system, neurotransmitter release, and related neurological pathways.
• Analytical Standard: Serves as a high-purity calibrant for HPLC, LC-MS, and other analytical methods in quality control laboratories.
• Chemical Synthesis: A versatile chiral synthon for organic chemists developing complex molecules with specific stereochemistry.

Basic Information

Product Name	(-)-3,4-Dihydroxynorephedrine
CAS No.	829-74-3
Molecular Formula	C9H13NO3
Molecular Weight	183.20 g/mol
Synonyms	(-)-α-(1-Aminoethyl)-3,4-dihydroxybenzyl alcohol; (1R,2S)-2-Amino-1-(3,4-dihydroxyphenyl)propan-1-ol; Norphenylephrine; (-)-Norphenylephrine; (R*,S*)-2-Amino-1-(3,4-dihydroxyphenyl)-1-propanol; α-Methylnorepinephrine; 6-Norepinephrine
EINECS	Contact for details

Quality Control

Our (-)-3,4-Dihydroxynorephedrine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles. We support compliance with relevant guidelines for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.