Description

Cyclopropylsulfonyl Fluoride is a specialized organosulfur compound featuring a reactive sulfonyl fluoride group attached to a cyclopropyl ring. This unique structure makes it a valuable high-purity building block in advanced chemical synthesis, particularly for applications requiring the introduction of the cyclopropyl moiety. It is primarily utilized by pharmaceutical researchers and agrochemical developers engaged in the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in medicinal chemistry programs targeting protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, and insecticides with potential enhanced efficacy and selectivity.
• Chemical Biology Probe Development: Serves as a reactive handle in activity-based protein profiling (ABPP) and the synthesis of covalent inhibitors for target identification and validation.
• Material Science Research: Employed in the synthesis of specialized monomers or polymers with unique properties derived from the strained cyclopropyl ring.
• Sulfonyl Fluoride Chemistry: Utilized in SuFEx (Sulfur Fluoride Exchange) click chemistry, a powerful tool for rapid and reliable molecular assembly in diverse fields.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in bespoke synthesis projects for clients in the life sciences sector.

Basic Information

Product Name	Cyclopropylsulfonyl Fluoride
CAS No.	822-49-1
Molecular Formula	C3H5FO2S
Molecular Weight	124.13 g/mol
Synonyms	Cyclopropanesulfonyl fluoride; Cyclopropylsulfonylfluoride; Sulfonyl fluoride, cyclopropyl-; Cyclopropyl sulfone fluoride; 1-Cyclopropylsulfonyl fluoride; Cyclopropane-1-sulfonyl fluoride; (Cyclopropylsulfonyl)fluoride
EINECS	Contact for details

Quality Control

Our Cyclopropylsulfonyl Fluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.