Description

Methyl Chlorosulfonate CAS NO 812-01-1 is a highly reactive organosulfur compound primarily used as a versatile sulfonating and chlorosulfonating agent in organic synthesis. Its value lies in its ability to introduce the methyl sulfonate or chlorosulfonyl group, enabling the production of specialty chemicals and advanced intermediates. This chemical is essential for research and development laboratories, pharmaceutical synthesis, and agrochemical manufacturing where precise functionalization is required.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for introducing sulfonate ester groups in active pharmaceutical ingredient (API) development.
• Agrochemical Production: Used in the manufacture of sulfonylurea-based herbicides and other crop protection agents.
• Dye and Pigment Chemistry: Employed as a sulfonating agent in the synthesis of sulfonated dyes and colorants.
• Polymer Modification: Facilitates the functionalization of polymers through sulfonation reactions to alter solubility or reactivity.
• Chemical Research: A valuable tool in academic and industrial R&D for constructing complex molecular architectures.
• Surfactant Precursor: Serves as a building block for specialized anionic surfactants and detergents.

Basic Information

Product Name	Methyl Chlorosulfonate
CAS No.	812-01-1
Molecular Formula	CH3ClO3S
Molecular Weight	130.55 g/mol
Synonyms	Methyl chlorosulfonate; Chlorosulfonic acid methyl ester; Methanesulfonyl chloride; Methylsulfonyl chloride; MSC; Methyl ester of chlorosulfonic acid; Methanesulphonic acid chloride; Methylchlorosulfonate
EINECS	212-359-8

Quality Control

Our Methyl Chlorosulfonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We adhere to current Good Manufacturing Practices (cGMP) where applicable, and our quality management system is designed to meet the stringent requirements of the pharmaceutical and fine chemical industries. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee supply reliability and technical compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, amines, and oxidizing agents. Due to its hygroscopic (moisture-sensitive) and strong acid/organic solvent nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	1.48 - 1.50 g/mL
Refractive Index (n20D)	1.450 - 1.455

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.