Description

1-Naphthalenesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation agent, facilitating the introduction of the naphthalenesulfonyl protecting group or the creation of sulfonamide linkages. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs), dyes, and functional materials.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of sulfonamide-based drugs and for introducing protective groups in complex molecule construction.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents that contain sulfonamide moieties.
• Dye and Pigment Manufacturing: Acts as an intermediate in the creation of sulfonated dyes and optical brighteners.
• Polymer Chemistry: Employed to modify polymers and create specialty monomers with specific sulfonyl functional groups.
• Bioconjugation and Proteomics: Useful in biochemical research for labeling proteins and other biomolecules.
• Organic Synthesis Reagent: A standard reagent for sulfonylation reactions in academic and industrial R&D laboratories.

Basic Information

Product Name	1-Naphthalenesulfonyl Chloride
CAS No.	85-46-1
Molecular Formula	C10H7ClO2S
Molecular Weight	226.68 g/mol
Synonyms	1-Naphthalenesulfonyl chloride; α-Naphthalenesulfonyl chloride; 1-Naphthylsulfonyl chloride; NSC 9790; Naphthalene-1-sulfonyl chloride; 1-Naphthalenesulphonyl chloride; α-Naphthalenesulfonyl chloride
EINECS	201-609-8

Quality Control

Our 1-Naphthalenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	66 - 70 °C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.