Description

Rottlerin CAS NO 82-08-6 is a potent and selective natural product inhibitor of protein kinase C delta (PKCδ). This compound is a critical research tool for elucidating cellular signaling pathways and has significant pharmacological interest. It is primarily utilized by researchers and developers in the life sciences sector for biochemical research, drug discovery, and the study of apoptosis and cancer mechanisms.

Application

• Biochemical Research: A selective inhibitor used to study the role of PKCδ in various cellular signaling cascades and disease models.
• Drug Discovery & Pharmacology: Serves as a lead compound or reference standard in the development of novel therapeutics targeting kinase-related disorders.
• Cancer Research: Investigated for its pro-apoptotic effects and potential anti-cancer properties in various cell line and animal studies.
• Neuroscience Studies: Used to explore PKCδ's function in neuronal signaling, degeneration, and neuroinflammatory processes.
• Cell Biology: Employed to modulate cellular processes such as secretion, proliferation, and differentiation in experimental setups.
• Reference Standard: Used as a high-purity analytical standard in quality control and method development for pharmaceutical analysis.

Basic Information

Product Name	Rottlerin
CAS No.	82-08-6
Molecular Formula	C30H28O8
Molecular Weight	516.54 g/mol
Synonyms	Mallotoxin; NSC 56317; 1-[6-[(3-Acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl]-3-phenyl-2-propen-1-one; Kamala compound; Rottlera; NSC-56317; PKCδ Inhibitor
EINECS	Contact for details

Quality Control

Our Rottlerin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to Brownish Powder
Identification (IR)	Conforms to Structure
Identification (HPLC)	Conforms to Reference
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.