Description

3-Chloro-2-Fluoro-4-Iodopyridine is a highly functionalized halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily utilized by pharmaceutical and agrochemical research organizations for the development of new active ingredients, including kinase inhibitors and other biologically relevant heterocycles.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and antiviral agents.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Building block for creating functionalized ligands, organic semiconductors, and liquid crystals.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Negishi couplings.
• Chemical Biology: Employed as a molecular probe or tag due to its halogen atoms, which can be used for further derivatization or labeling.
• Academic & Contract Research: Essential reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	3-Chloro-2-Fluoro-4-Iodopyridine
CAS No.	796851-05-3
Molecular Formula	C5H2ClFIN
Molecular Weight	273.43 g/mol
Synonyms	3-Chloro-2-fluoro-4-iodopyridine; 2-Fluoro-3-chloro-4-iodopyridine; 4-Iodo-3-chloro-2-fluoropyridine; Pyridine, 3-chloro-2-fluoro-4-iodo-; 796851-05-3; 3-Chloro-2-fluoro-4-iodo-pyridine
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluoro-4-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/GC-MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.