Description

1H-Pyrazole-4-Carboxamide, n-[5-[(Cyclopropylamino)Carbonyl]-2-Methylphenyl]-5-Methyl-1-[3-(Trifluoromethyl)-2-Pyridinyl]- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in targeted drug discovery programs. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers specializing in active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for small molecule therapeutics.
• Kinase Inhibitor Research: Serves as a core scaffold or precursor in the development of protein kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its pyrazole and trifluoromethylpyridine motifs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for clinical trial materials.
• Biochemical Research: Employed as a tool compound or ligand in biochemical assays to study specific enzyme interactions and pathways.
• High-Value Fine Chemical Production: Integral in multi-step synthetic routes for producing complex, high-value specialty chemicals.

Basic Information

Item	Details
Product Name	1H-Pyrazole-4-Carboxamide, n-[5-[(Cyclopropylamino)Carbonyl]-2-Methylphenyl]-5-Methyl-1-[3-(Trifluoromethyl)-2-Pyridinyl]-
CAS No.	796069-97-1
Molecular Formula	C23H22F3N5O2
Molecular Weight	457.45 g/mol
Synonyms	N-[5-[(Cyclopropylamino)carbonyl]-2-methylphenyl]-5-methyl-1-[3-(trifluoromethyl)pyridin-2-yl]-1H-pyrazole-4-carboxamide; 1H-Pyrazole-4-carboxamide, N-[5-[(cyclopropylamino)carbonyl]-2-methylphenyl]-5-methyl-1-[3-(trifluoromethyl)-2-pyridinyl]-; UNII-1JQ8K9F5V0; 1JQ8K9F5V0; CHEMBL3186036; BDBM50157873; HY-134098; AKOS025147324
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and LC-MS. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.