Description

(5-Trifluoromethyl-Pyridin-2-Yl)-Acetic Acid CAS NO 785762-99-4 is a high-value pyridine derivative and trifluoromethylated building block essential for modern synthetic chemistry. Its core value lies in enabling the precise introduction of a metabolically stable trifluoromethyl group and a versatile acetic acid side chain into complex molecular architectures. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and electronic materials that require specific fluorine-containing motifs.
• Custom Synthesis & Contract Research: A vital starting material for custom synthesis organizations (CSOs) and R&D labs working on proprietary compounds for clients.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags to study biological processes and protein interactions.

Basic Information

Product Name	(5-Trifluoromethyl-Pyridin-2-Yl)-Acetic Acid
CAS No.	785762-99-4
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	2-(5-(Trifluoromethyl)pyridin-2-yl)acetic acid; [5-(Trifluoromethyl)-2-pyridyl]acetic Acid; 5-(Trifluoromethyl)picolinic Acid, Acetic Acid Derivative; (5-Trifluoromethyl-2-pyridyl)acetic Acid; 2-Pyridineacetic acid, 5-(trifluoromethyl)-; α-Carboxymethyl-5-trifluoromethylpyridine; 5-Trifluoromethyl-2-pyridylacetic Acid; TFMPAA
EINECS	Contact for details

Quality Control

Our (5-Trifluoromethyl-Pyridin-2-Yl)-Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring research-grade to development-scale materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is a strong acid/organic solvent and should be stored separately from bases and oxidizing agents. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.