Description

2-Fluoro-5-(1H-Imidazol-4-Yl)-Pyridine is a high-value heterocyclic building block that combines pyridine and imidazole pharmacophores. This compound matters as a critical intermediate in modern pharmaceutical research and development, enabling the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and biotechnology industries for creating targeted drug candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides and fungicides.
• Biochemical Probe Synthesis: Utilized to develop tool compounds for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.
• Academic Research: Employed in university and institutional labs for heterocyclic chemistry and drug discovery projects.

Basic Information

Product Name	2-Fluoro-5-(1H-Imidazol-4-Yl)-Pyridine
CAS No.	780749-63-5
Molecular Formula	C8H6FN3
Molecular Weight	163.15 g/mol
Synonyms	2-Fluoro-5-(1H-imidazol-4-yl)pyridine; 5-(1H-Imidazol-4-yl)-2-fluoropyridine; 2-Fluoro-5-(imidazol-4-yl)pyridine; 4-(6-Fluoropyridin-3-yl)-1H-imidazole; 780749-63-5; 2-Fluoro-5-(1H-imidazol-4-yl)pyridine; 2-Fluoro-5-(4-imidazolyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-(1H-Imidazol-4-Yl)-Pyridine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.