Description

4-Methoxy-2-(trifluoromethyl)benzenesulphonylchloride is a high-purity, specialized sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its dual functional groups—the sulfonyl chloride and the electron-donating methoxy group—which enable precise and efficient derivatization for creating complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients, intermediates, and fine chemicals requiring specific sulfonamide or sulfonate functionalities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the development of specialty polymers, dyes, and liquid crystals where sulfonyl groups modify material properties.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new reaction pathways and creating custom chemical libraries.
• Active Pharmaceutical Ingredient (API) Development: Integral in constructing the core scaffold of potential APIs targeting various therapeutic areas.

Basic Information

Product Name	4-Methoxy-2-(Trifluoromethyl)Benzenesulphonylchloride
CAS No.	775288-85-2
Molecular Formula	C8H6ClF3O3S
Molecular Weight	274.64 g/mol
Synonyms	2-(Trifluoromethyl)-4-methoxybenzenesulfonyl chloride; 4-Methoxy-α,α,α-trifluoro-o-toluenesulfonyl chloride; 2-Trifluoromethyl-4-methoxybenzenesulfonyl chloride; 4-Methoxy-2-trifluoromethylbenzenesulfonyl chloride; 1-Methoxy-4-(trifluoromethyl)benzene-2-sulfonyl chloride; p-Methoxy-o-(trifluoromethyl)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-Methoxy-2-(trifluoromethyl)benzenesulphonylchloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We operate under a quality management system and can support compliance requirements for cGMP, ISO, and other relevant regulatory standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.