Description

3-Pyridineacetonitrile, 6-(Trifluoromethyl)- is a high-value, fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique combination of the pyridine scaffold and the trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients. We supply this material with a focus on high purity, batch-to-batch consistency, and reliable global logistics to support your R&D and scale-up projects.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials that require fluorinated aromatic components.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological pathways and target engagement.

Basic Information

Product Name	3-Pyridineacetonitrile, 6-(Trifluoromethyl)-
CAS No.	765298-04-2
Molecular Formula	C8H5F3N2
Molecular Weight	186.14 g/mol
Synonyms	6-(Trifluoromethyl)pyridine-3-acetonitrile; 2-[6-(Trifluoromethyl)pyridin-3-yl]acetonitrile; 3-Pyridineacetonitrile, 6-(trifluoromethyl)-; 6-(Trifluoromethyl)-3-pyridineacetonitrile; (6-(Trifluoromethyl)pyridin-3-yl)acetonitrile; 2-(6-(Trifluoromethyl)pyridin-3-yl)acetonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridineacetonitrile, 6-(Trifluoromethyl)- undergoes rigorous analytical testing to ensure it meets the high standards required for synthetic applications. Our quality protocols include identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment, ensuring full traceability and compliance with your internal quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.