Description

3-Bromo-2-(2,2,2-trifluoro-ethoxy)-pyridine is a high-value, halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its unique trifluoroethoxy and bromo substituents, which are instrumental in modulating the physicochemical and biological properties of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine and bromine atoms contribute to enhanced biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized organic materials and liquid crystals due to its distinct electronic properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Bromo-2-(2,2,2-trifluoro-ethoxy)-pyridine
CAS No.	760207-89-4
Molecular Formula	C7H5BrF3NO
Molecular Weight	256.02 g/mol
Synonyms	2-(3-Bromopyridin-2-yloxy)-1,1,1-trifluoroethane; 3-Bromo-2-[(2,2,2-trifluoroethyl)oxy]pyridine; 3-Bromo-2-(2,2,2-trifluoroethoxy)pyridine; Pyridine, 3-bromo-2-(2,2,2-trifluoroethoxy)-; 760207-89-4; 3-Bromo-2-(trifluoroethoxy)pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-(2,2,2-trifluoro-ethoxy)-pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.