Description

2-Pyridineacetic Acid, 5-(Trifluoromethyl)-, Ethyl Ester is a high-value trifluoromethylated pyridine derivative, a crucial building block in advanced organic synthesis. Its core value lies in the unique combination of the pyridine heterocycle and the electron-withdrawing trifluoromethyl group, which is essential for modulating the physicochemical properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals or organic semiconductors, where its structural motifs can influence electronic properties.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes and tags used in biochemical assays and diagnostic research.

Basic Information

Product Name	2-Pyridineacetic Acid, 5-(Trifluoromethyl)-, Ethyl Ester
CAS No.	757971-25-8
Molecular Formula	C10H10F3NO2
Molecular Weight	233.19 g/mol
Synonyms	Ethyl 5-(Trifluoromethyl)pyridin-2-ylacetate; 2-Pyridineacetic acid, 5-(trifluoromethyl)-, ethyl ester; 5-(Trifluoromethyl)-2-pyridineacetic acid ethyl ester; Ethyl (5-(trifluoromethyl)pyridin-2-yl)acetate; (5-Trifluoromethyl-pyridin-2-yl)-acetic acid ethyl ester; 2-(5-Trifluoromethyl-2-pyridyl)acetic acid ethyl ester; Ethyl 2-(5-(trifluoromethyl)pyridin-2-yl)acetate
EINECS	Contact for details

Quality Control

Our 2-Pyridineacetic Acid, 5-(Trifluoromethyl)-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.